A better way to model cancer

By Gunjan Sinha

Later this year, the first US-based clinical trial to test whether an organoid model of prostate cancer can predict drug response will begin recruiting patients. Researchers will grow the organoids—miniorgans coaxed to develop from stem cells—from each patient’s cancer tissues and expose the organoids to the patient’s planned course of therapy. If the organoids mirror patients’ drug responses, the results would support the model’s use as a tool to help guide therapy.

How well do you know the Hollywood musical? [quiz]

In Hollywood Aesthetic: Pleasure in American Cinema, film studies professor Todd Berliner explains how Hollywood delivers aesthetic pleasure to mass audiences. The following quiz is based on information found in chapter 11, “Bursting into Song in the Hollywood Musical.”

Presidential pensions as broken windows

By Edward A. Zelinsky

The complex (and often tragic) saga of post-presidential retirements is well-known. Some presidents, such as Herbert Hoover, were independently-wealthy and thus spent their years after the White House in economic security. Other presidents, such as Woodrow Wilson, lived only briefly after their service in the Oval Office. Yet other former presidents experienced great financial difficulties in retirement.

Saving old forests

By Yves Bergeron, Alain Leduc, and Frederic Raulier

Research shows that boreal forests, like those across much of Northern Europe and Canada, have higher levels of variability in their structure and dynamics when unmanaged, improving their biodiversity and the stability of their ecosystems. These unmanaged forests also have a higher proportion of older trees than those used in industrial forest rotation – around 70-100 years in Canadian boreal forests.

Church and nature: sex and sin

By Valerie Minogue

The Sin of Abbé Mouret reworks the Genesis story of the Fall of Man, with the abbé, Serge Mouret as Adam, and the young Albine his Eve. Fifth of the twenty novels of Zola’s Rougon-Macquart cycle, the novel follows on almost directly from The Conquest of Plassans, in which the young Serge Mouret decides to become a priest.

An economist views the UK’s snap general election

By Jan Toporowski

There is something unusual about the 2017 UK general election. It is the way in which all the manifestos clearly make their promises conditional on the ‘good Brexit deal’ that they claim to be able to secure. They are not the only ones. On 11 May the Governor of the Bank of England Mark Carney reassured the markets that the ‘good Brexit deal’ would stabilise our economy after 2019, and the markets were duly sedated.

En Marche: Macron’s France and the European Union

By Anthony Pagden

On the evening of 7 May, Emmanuel Macron walked, almost marched, slowly across the courtyard of the Louvre to make his first speech as the President elect of the French Fifth Republic. He did so not, as others would have done, to the music of the “Marseillaise” but to the final movement of Beethoven’s Ninth Symphony – the “Ode to Joy”, the anthem of the European Union. It was, wrote Natalie Nougayrède in the Guardian, “the most meaningful, inspiring symbol Macron could choose”.

Using novel gas observations to probe exocomet composition

By Quentin Kral

Space missions like the Rosetta space probe built by the European Space Agency, that recently reached and studied the comet 67P/Churyumov-Gerasimenko, address the profound question of how life came to Earth by quantifying the composition of comets in the Solar System. Comets are made of the pristine material from which planets were formed. By exploring the composition of comets, we can thus access the pristine composition of the building blocks of planets.

Flying kites: politics, elections, and The One Show

By Matthew Flinders

Apparently there is a Chinese proverb that says ‘unless there is opposing wind, a kite cannot rise’ but in the context of British politics it appears that only one kite is really rising, and the other is tumbling down. If truth be told the wind of opposition has arguably been so feeble that the Labour Party’s kite appears leaden rather than light.

How to use repetition

By Edwin Battistella

A couple times a week, I hear someone remark “It is what it is,” accompanied by a weary sigh. I always puzzle over the expression a little bit, thinking What else could it be?

Business as usual in Washington?

By Miriam A. Golden and Ray Fisman

While these behaviors may be no more troubling to a large swath of the electorate in the United States than revolving door lobbyists or campaign finance run amok, they should be. Some legal scholars contend that cumulatively, Trump’s actions may well violate the emoluments clause of the US Constitution. Taken individually, however, none of his actions seem likely to be illegal or corrupt.

Are Indians charitable?

By Pushpa Sundar

Are Indians charitable? My answer to this question is yes, as much as any other, contrary to what international surveys may maintain. I believe India comes out poorly on the generosity index because the focus is on aggregated giving and no distinction is being made between philanthropic giving and charitable giving. My contention is that charity is alive and well in India, and Indians are as charitable as any other nation.

Philosopher of the month: Swami Vivekānanda [timeline]

By Catherine Pugh and John Priest

This June, the OUP Philosophy team honors Swami Vivekānanda (born Narendranath Datta, 1863–1902) as their Philosopher of the Month. Born in Calcutta under colonial rule, Vivekānanda became a Hindu religious leader, and one of the most prominent disciples of guru and mystic Śri Rāmakṛṣṇa.

A glimpse at Eclipse 2017 [excerpt]

By Frank Close

Anyone who has experienced the diamond ring effect that heralds the start of a total solar eclipse will tell you that it is the most beautiful natural phenomenon that they have ever seen.

A reading list for Euroanaesthesia 2017 in Geneva

By Pete Ward

This weekend anaesthetists from across the globe are descending upon Geneva for Euroanaesthesia, Europe’s largest annual event focusing on anaesthesia, perioperative medicine, intensive care, emergency medicine, and pain treatment. We’ll be heading out there too, and the interactive bookcase below will give you a sneak peek at what we’ll have available at stand 81a!

Net neutrality and the new information crossroads

By James W. Cortada

Despite the rapidly expanding collections of information, the nation’s information is at risk. As more of it comes in digitized form and less in printed or verbalized formats, it can be corralled and viewed more easily by groups or institutions concerned with only their interests.