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Academic Insights for the Thinking World

Beethoven’s diagnosis

Since Beethoven’s death on this day 188 years ago, debate has raged as to the cause of his deafness, generating scores of diagnoses ranging from measles to Paget’s disease. If deafness had been his only problem, diagnosing the disorder might have been easier, although his ear problem was of a strange character no longer seen. It began ever so surreptitiously and took over two decades to complete its destruction of Beethoven’s hearing.

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Purple Day: a day for thinking about people with epilepsy

Purple Day started with the curiosity and of a girl in eastern Canada, in the province of Nova Scotia, who had epilepsy. It soon became a world-wide success. Purple Day is now an international initiative and effort dedicated to increasing awareness about epilepsy around the globe. Why is it so important to create awareness around people with epilepsy?

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Oxford Medicine Online

The history of epilepsy: an interactive timeline

Investigations into the nature of epilepsy, and its effects on those diagnosed with the disorder, can be traced back for almost 2,000 years. From associations with lunar cycles, to legislation preventing those with epilepsy to marry, the cultural and scientific record on epilepsy treatment is one of stigma and misunderstanding.

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Where do drugs come from? [quiz]

The discovery and development of drugs was not always a straight path. Many times, the drugs that are well-known today — both hallucinogenic and medicinal — were discovered by mistake or originally developed for a much different purpose. How well do you know the history of some of the most common drugs? Take this quiz to find out if you can match the drug to its origin.

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Chlamydia: a global health question?

A leading researcher in the field of immunogenetics, Servaas Morré has investigated women’s genetic susceptibilities to Chlamydia trachomatis, recently co-authoring “NOD1 in contrast to NOD2 functional polymorphism influence Chlamydia trachomatis infection and the risk of tubal factor infertility.” We sat down with Morré to discuss his findings about the most common sexually transmitted bacterial infection and the impact his research will have on treatment in the years to come.

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Clinical placement in Nepal: an interview with Ruth Jones

In May last year, Oxford Handbook of Clinical Medicine, in partnership with Projects Abroad, offered one lucky medical student the chance to practice their clinical skills abroad in an international placement. The winner was Ruth Jones from the University of Nottingham, who impressed the judging panel with her sincerity, dedication, and willingness to become the best doctor she can be.

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Preparing for the next Ebola

As Ebola recedes from the headlines, amid long awaited declines in incidence in West Africa, a long overdue commitment to developing vaccines and adequate health care infrastructure is underway. The importance of these approaches should not to be minimized.

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Excellence in residency education

A middle-aged man was recently admitted to a Midwest hospital for “refractory congestive heart failure.” He had been followed in the hospital’s out-patient clinic for two years with that diagnosis. Yet, he continued to retain fluid and gain weight, despite optimal treatment for congestive heart failure.

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Living with the Stars – Episode 20 – The Oxford Comment

Everything is connected. Animals and asteroids, bodies and stardust, heart valves and supernovas—all of these rise from the same origin to form the expanse of the universe, the fiber of our being. So say our guests of this month’s Oxford Comment, Karel Shrijver, an astronomer who studies the magnetic fields of stars, and Iris Schrijver, a physician and pathologist. We sat down for a captivating discussion with the co-authors of Living with the Stars: How the Human Body is Connected to the Life Cycles of the Earth, the Planets, and the Stars.

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The IOM’s effort to dislodge chronic fatigue syndrome

The Institute of Medicine (IOM) recently released their report regarding a new name (i.e., systemic exertion intolerance disease) and case definition for chronic fatigue syndrome (CFS). In brief, the IOM proposed that at least four symptoms needed to be present to be included in this new case definition […]

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Let’s finally kick the habit: governance of addictions in Europe

More than a century ago, on 23 January 1912, the first international convention on drug control was signed in The Hague. A century later, despite efforts made at all levels and vast quantities of evidence, our societies still struggle to deal effectively with addictive substances and behaviours. Reaching a global consensus has proved harder than kicking the worst drug-taking habit.

Nonetheless, the meeting of the Global Commission on Drug Policy held on 9 September 2014 in New York might be a turning point.

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The sombre statistics of an entirely preventable disease

Sore throats are an inevitable part of childhood, no matter where in the world one lives. However for those children living in poor, under-resourced and marginalised societies of the world, this could mean a childhood either cut short by crippling heart failure or the need for open-heart surgery.

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The important role of palatable food in eating disorders

When we hear the term “eating disorder,” we often think of the woman at our gym who looks unhealthily thin or maybe a friend who meticulously monitors each calorie he or she consumes. Though anorexia nervosa (marked by low weight and a strong fear of weight gain) is a serious and harmful mental illness with one of the highest mortality rates of any psychiatric illness, the reality is that the most common eating disorders are bulimia nervosa and binge eating disorder, both of which involve (and in fact, require for their diagnosis) binge eating.

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Why are some residency programs better than others?

Considerable variation in quality exists among residency programs in the United States, even among those in the same specialty, such as surgery, pediatrics, or internal medicine. Some are nationally and internationally renowned, others are known regionally, and still others are known only locally.

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How disease names can stigmatize

On 10 February 2015, the long awaited report from the Institute of Medicine (IOM) was released regarding a new name — Systemic Exertion Intolerance Disease — and case definition for chronic fatigue syndrome (CFS). Because I was quoted regarding this report in a New York Times article, in part due to having worked on these issues for many years, hundreds of patients contacted me over the next few days.

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