Oxford University Press's
Academic Insights for the Thinking World

The sombre statistics of an entirely preventable disease

Sore throats are an inevitable part of childhood, no matter where in the world one lives. However for those children living in poor, under-resourced and marginalised societies of the world, this could mean a childhood either cut short by crippling heart failure or the need for open-heart surgery.

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The important role of palatable food in eating disorders

When we hear the term “eating disorder,” we often think of the woman at our gym who looks unhealthily thin or maybe a friend who meticulously monitors each calorie he or she consumes. Though anorexia nervosa (marked by low weight and a strong fear of weight gain) is a serious and harmful mental illness with one of the highest mortality rates of any psychiatric illness, the reality is that the most common eating disorders are bulimia nervosa and binge eating disorder, both of which involve (and in fact, require for their diagnosis) binge eating.

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Why are some residency programs better than others?

Considerable variation in quality exists among residency programs in the United States, even among those in the same specialty, such as surgery, pediatrics, or internal medicine. Some are nationally and internationally renowned, others are known regionally, and still others are known only locally.

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How disease names can stigmatize

On 10 February 2015, the long awaited report from the Institute of Medicine (IOM) was released regarding a new name — Systemic Exertion Intolerance Disease — and case definition for chronic fatigue syndrome (CFS). Because I was quoted regarding this report in a New York Times article, in part due to having worked on these issues for many years, hundreds of patients contacted me over the next few days.

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February is Heart Month

February is Heart Month in both the United States and the United Kingdom. It is a time to raise awareness of heart and circulatory diseases. Heart Month highlights all forms of heart disease, from certain life-threatening heart conditions that individuals are born with, to heart attacks and heart failure in later life.

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Antibody cancer therapy: a new age?

In 1998 the biotech company Genentech launched Herceptin for the treatment of certain types of breast cancer. Herceptin was an example of a ‘therapeutic antibody’ and was the first of its type for cancer treatment. Antibodies are proteins in our immune system that can target abnormal cells (or bacteria, toxins, viruses, etc.) in the body, and on arriving at the target can set in motion a whole set of biological events that in principle can remove or degrade to a non-dangerous state the abnormal cells.

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Ethical issues in developing scales for biomedical research

When we think of ethical issues in bio-medical research (if we think of them at all), what usually comes to mind are either egregious breaches, such as the infamous Tuskegee syphilis study, in which treatment was kept from rural black men in order to investigate the natural history of this treatable disease, or questions such as whether it is proper to use prisoners as subjects in early drug testing trials.

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Fluorescent proteins and medicine

Fluorescent proteins are changing the world. Page through any modern scientific journal and it’s impossible to miss the vibrant images of fluorescent proteins. Bright, colorful photographs not only liven-up scholarly journals, but they also serve as invaluable tools to track HIV, to design chickens that are resistant to bird flu and to confirm the existence of cancerous stem cells.

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Oxford Medicine Online

Public health in 2014: a year in review

With the Ebola virus outbreak, great debate surrounding electronic cigarettes, and other public health topics in the media headlines, 2014 was a very eventful year for public health. The year also brought many great research articles, blogs, and publications addressing these and other important issues.

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Which health messages work?

Is it better to be positive or negative? Many of the most vivid public health appeals have been negative – “Smoking Kills” or “Drive, Drive, and Die” – but do these negative messages work when it comes to changing eating behavior?

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Have we become what we hate?

In 1971, William Irvin Thompson, a professor at York University in Toronto, wrote an op-ed in the New York Times entitled, “We Become What We Hate,” describing the way in which “thoughts can become inverted when they are reflected in actions.” He cited several scientific, sociocultural, economic, and political situations where the maxim appeared to be true. The physician who believed he was inventing a pill to help women become pregnant had actually invented the oral contraceptive.

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Textbook of Post-ICU Medicine

Working in the intensive care unit: an interview with Dr. Robert Stevens

When patients are discharged from the intensive care unit it’s great news for everyone. However, it doesn’t necessarily mean the road to recovery is straight. As breakthroughs and new technology increase the survival rate for highly critical patients, the number of possible further complications rises, meaning life after the ICU can be complex.

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An interactive timeline of the history of anaesthesia

The field of anaesthesia is a subtle discipline, when properly applied the patient falls gently asleep, miraculously waking-up with one less kidney or even a whole new nose. Today, anaesthesiologists have perfected measuring the depth and risk of anaesthesia, but these breakthroughs were hard-won.

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What is it like to be depressed?

How are we to understand experiences of depression? First of all, it is important to be clear about what the problem consists of. If we don’t know what depression is like, why can’t we just ask someone who’s depressed?

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