Oxford University Press's
Academic Insights for the Thinking World

Modern life and clinical psychology

It’s a sad but very modern paradox. Despite the many wonderful opportunities and options like education, technologies, internet resources and travel that are open to young people today, young people’s mental health today has never been so fragile. In contrast to the frequently portrayed images of happy, successful, and socially connected millennials in selfies, in fact many millennials seem to feel more empty and lost than ever.

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Are the microbes in our gut affecting how fast we age?

The collection of microbial life in the gut, known as the microbiota, may be considered an accessory organ of the gastrointestinal tract. It is a self-contained, multi-cellular, biochemically active mass with specialized functions. Some functions are important for life such as vitamin K synthesis, an essential molecule in blood clotting. Others are responsible for training and maintaining a healthy immune system or digesting indigestible food products such as insoluble fiber.

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Debating the right to die

There are so many reasons why we value and promote choice and autonomy. The country and news media quite rightly protests with outrage when bad things happen to good people as their lives and civil liberties are destroyed by acts of terrorism and grievous crimes. But what about all those many people who are living a life in situations they didn’t want or anticipate?

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Is epigenomics the next breakthrough in precision medicine?

Epigenomics holds a lot of promise for cancer treatments, but there are still many more questions that we need to answer. How does the epigenome of a healthy person look, and how does the epigenome change as we age? How does the epigenome of a sick person differ? In the future, these important questions will be addressed by personalized epigenomics, which tries to extract information out of a comprehensive picture of a person’s epigenome.

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On the origins of “dad bod”

A few years back the phrase “dad bod” emerged to describe men, especially fathers, who have hints of lean muscle lurking beneath noticeable body fat, perhaps particularly around their bellies. There’s increasing evidence that men in industrialized countries like the United States tend to gain weight after they move in with a partner, marry, or become parents, lending some credence to the “dad” in dad bod.

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The modern marvel of medicine

So, where does the future lie in the specialty of anaesthesia? Equipment and monitoring will become more sophisticated with the ultimate aim to minimise harm to patients. It is likely that robotics will be integrated within the patient’s surgical pathway to reduce human error and optimise efficiency of care. Newer drugs will be synthesized with fewer adverse effects and complications.

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Preventing misdiagnosis of intracranial pressure disorders on diagnostic imaging

Imaging can build a stronger case for a specific diagnosis when several findings associated with that condition are present, making it important for those interpreting the images to be aware of the full scope of imaging findings in each ICP disorder. Finally, open and constructive communication between radiologists and clinical specialists is key to correct diagnosis, starting with appropriate clinical information

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Understanding stress and anxiety

Almost everybody experiences some stress and associated anxiety on a regular basis. While not particularly comfortable, these reactions can be valuable in alerting us to pay extra attention when we perform important tasks or find ourselves in high-risk situations. Sometimes, however, the stress response is triggered too easily or too intensely, causing unnecessary discomfort. In these cases, it helps to learn techniques to regulate the stress response.

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Wearable health trackers: a revolution in cancer care

Activity trackers, wearable electronics that collect data passively and can be worn on the body, infiltrated the world’s fitness market in the last decade. Those devices allowed consumers to track steps and heart rate. Next, wearable devices overtook the chronic illness market, giving patients the power to track health behavior and adherence to medication, which could be easily reported back to doctors.

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Bugs don’t recognize nationality

Microbes have not yet met an ocean, wall, or national border they could not permeate. Zika once again has demonstrated that large and small countries, relatively wealthy and relatively poorer countries all are dependent on a larger infrastructure for their national health security – even the United States cannot rely solely on itself to fight an outbreak or protect itself and Americans from the next outbreak.

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On the physicality of racism

When you talk about how the young boys that I grew up around walked through the world, when you talk about the fact that my brother had made a decision at 13 that he was going to carry a handgun, when you talk about the fact that that wasn’t even unusual, you are talking about the physical safety, the danger, the very health of the body. Conversations about race are filled with words and euphemisms to describe the impact of racism on people and communities.

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Supporting and managing global health

Around the world, health is among the most important issue facing individuals, communities, governments, and countries as a whole. While there are increases in policy debates and developments in medical research, there are still many actions that can be taken to improve the picture of health at a global level. Following an event at Columbia University, we sat down with Chelsea Clinton and Devi Sridhar, authors of Governing Global Health

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Is privacy the price of precision medicine?

New initiatives aim to harness technology and genomics to create bespoke medicine, customizing your healthcare like your Facebook profile. Instead of relying on generic practice guidelines, your doctors may one day use these new analytic tools to find the ideal treatment for you. Big data will make this precision possible: patterns that emerge from the DNA and medical records of millions can predict which treatments work best for which patients.

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Mitochondrial replacement techniques and Mexico

The birth of the the first child after a mitochondrial replacement technique has raised questions about the legality of such procedure. In this post we explore some of the legal issues surrounding this case. Mitochondria are cellular organelles that generate the energy cells need to work properly. Two interesting features of mitochondria are that they are solely inherited via the maternal line and that they possess their own DNA.

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Facts about sanitation and wastewater management

After oxygen, fresh, clean water is the most basic requirement for the majority of life on Earth in order to survive. However, this is a true luxury that isn’t accessible for many millions of people around the world. Today hundreds of thousands of people die every year from these types of waterborne diseases, and even though these numbers are declining there is still work to be done.

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It’s time we talked about transport of the critically ill

Ever stopped at the scene of an accident on a dark night? Treated a heart attack on a remote island? Coordinated the transfer of a critically ill baby with a heart defect? Were you prepared? Did you have the right toolkit? You need a cool head to perform critical clinical interventions while simultaneously planning the transfer to definitive care. Almost all patients have a transport phase

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