2016 is a leap year. A leap year, or intercalary year, is a year with an extra day inserted to keep pace with the seasons. In the Gregorian calendar this falls every four years on Feb 29th. On Leap Day this year a wonderful piece of science was published about an equally rare part of nature – giant viruses.
Announced on January 13th by President Obama in his eighth and final State of the Union Address, the multi-billion dollar project will be led by US Vice President, Joe Biden, who has a vested interest in seeing new cures for cancer. Using genomics to cure cancer is being held on par with JFK’s desire in 1961 to land men on the moon.
2016 is here. The New Year is a time for renewal and resolution. It is also a time for dieting. Peak enrolment and attendance times at gyms occur after sumptuous holiday indulgences in December and again when beach wear is cracked out of cold storage in summer. As the obesity epidemic reaches across the globe we need new solutions. We need better ways to live healthy lifestyles.
Knowledge that we all have DNA and what this means is getting around. The informed public is well aware that our cells run on DNA software called the genome. This software is passed from parent to child, in the long line of evolutionary history that dates back billions of years – in fact, research published this year pushes back the origin of life on Earth another 300 million years.
It is hard to quantify the impact of ‘role-model’ celebrities on the acceptance and uptake of genetic testing and bio-literacy, but it is surely significant. Angelina Jolie is an Oscar-winning actress, Brad Pitt’s other half, mother, humanitarian, and now a “DNA celebrity”. She propelled the topic of familial breast cancer, female prophylactic surgery, and DNA testing to the fore.
Society owes a debt to Henrietta Lacks. Modern life benefits from long-term access to a small sample of her cells that contained incredibly unusual DNA. As Rebecca Skloot reports in her best-selling book, The Immortal Life of Henrietta Lacks, the story that unfolded after Lacks died at the age of 31 is one of injustice, tragedy, bravery, innovation and scientific discovery.
Kuwait is changing the playing field. In early July, just days after the June 26th deadly Imam Sadiq mosque bombing claimed by ISIS, Kuwait ruled to instate mandatory DNA-testing for all permanent residents. This is the first use of DNA testing at the national-level for security reasons, specifically as a counter-terrorism measure. An initial $400 million dollars is set aside for collecting the DNA profiles of all 1.3 million citizens and 2.9 million foreign residents
Today, the amount of global genetic data is doubling on the order of every seven months. This time span has shortened significantly over the past years as the field of genomics continues to mature. A recent study showed genomics is starting to compete with the data outputs of digital giants like Twitter and YouTube.
Another ‘Awareness Day’, International Kissing Day, is coming up on July 6. It might not seem obvious but kissing, like most subjects can now be easily linked to the science of DNA. Thus, there could be no more perfect opener for my Double Helix column, given the elegance and beauty of a kiss. To start, there is the obvious biological link between kissing and DNA: propagation of the species. Kissing is not only pleasurable but seems to be a solid way to assess the quality and suitability of a mate.
One of the most fun and exciting sources of information available for free on the Internet are the videos found on the Technology, Entertainment and Design (TED) website. TED is a hub of stories about innovation, achievement and change, each artfully packaged into a short, highly accessible talk by an outstanding speaker. As of April 2015, the TED website boasts 1900+ videos from some of the most imminent individuals in the world. Selected speakers range from Bill Clinton and Al Gore to Bono and other global celebrities to a range of academics experts.
DNA is the foundation of life. It codes the instructions for the creation of all life on Earth. Scientists are now reading the autobiographies of organisms across the Tree of Life and writing new words, paragraphs, chapters, and even books as synthetic genomics gains steam. Quite astonishingly, the beautiful design and special properties of DNA makes it capable of many other amazing feats. Here are five man-made functions of DNA, all of which are contributing to the growing “industrial-DNA” phenomenon.
Did you see ‘blue and black’ or ‘white and gold’? Or did you miss the ‘dress-capade’ that exploded the Internet last month? It was started by this post on Tumblr that went viral. Many people warned their heads risked exploding in disbelief. How could people see the same dress in different colours? It appears the variation lies in the way we judge how light reflects off objects of different colours, as Harvard psychologist Steven Pinker explained in Forbes. A follow-on, calmer discussion started about whether this trait could be in our DNA.
A Practical Genomics Revolution is rolling out, owing to the dropping cost of DNA sequencing technology, accelerated DNA research, and the benefits of applying genetic knowledge in everyday life. We now have ‘million-ome’ genome sequencing projects and talk of ‘billion-omes’ is growing audible. Given the expense – even at only $1000 a genome, a million still costs $1 billion US dollars — it is only right to ask, “What will the impact be?”
Watching the field of genomics evolve over the past 20 years, it is intriguing to notice the word “genome” cozying up to the word ‘million’. Genomics is moving beyond 1k, 10k and 100k genome projects. A new courtship is blossoming. The Obama Administration has just announced a Million Genomes Project – and it’s not even the first. Now both Craig Venter and Francis Collins, leads of the private and public versions of the Human Genome Project, are working on their million-omes.
NHS England is creating 11 Genomic Medicine Centres designed to deliver its ambitious 100,000 Genomes Project. In the broader sense it is an undeniable sign that genomics is poised to transform human medicine by improving the efficacy of medical diagnosis and personalized treatment. This is a major step in the implementation of the Genomics England […]