To mark the release of Vanishing Bone, in Part One of our Q&A with Dr. William H. Harris we discussed the fascinating story of how he came to identify, and later cure, the severe bone destruction affecting individuals who had undergone total hip replacement surgery. In this second interview, Dr. Harris reflects on his remarkable career; including what inspired him to pursue orthopaedic surgery, how he balances his two roles as a surgeon and clinician-scientist, and his advice for aspiring surgeons.
When orthopaedic surgeon, Dr. William H Harris discovered massive bone destruction around a total hip replacement that he had implanted, he was startled and dismayed. In fact, he had identified a new condition, “periprosthetic osteolysis”, which came to be the leading factor in failure of total hip replacement (THR) surgery. While THR surgery dramatically reversed severe arthritis of the hip, the same operation simultaneously created a relentless “particle generator” in the body.