Oxford University Press's
Academic Insights for the Thinking World

  • Author: David M. Greer

Randomized controlled trials: Read the “fine print”!

Most randomized controlled trials (RCTs) can appear deceptively simple. Study subjects are randomized to experimental therapy or placebo—simple as that. However, this apparent simplicity can mask how important subtle aspects of study design—from patient selection to selected outcomes to trial execution—can sometimes dramatically affect conclusions.

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