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Cancer virus: the eureka moment

By Dorothy Crawford
On 24 February 1964 a young research virologist at the Middlesex Hospital in London peered at the screen of an electron microscope and saw a new virus. It turned out to be a human cancer virus – the first ever discovered.

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Serendipity in science

By Dorothy Crawford
Chance is a fine thing, especially when it leads to a major new discovery. Remarkably, this often seems to be the case with scientific discoveries, at least in my field – tumour virology. We now know that around 20% of cancers are caused by microbes but without chance this figure might be substantially lower. The first human tumour virus was discovered in 1964 by Anthony Epstein and Yvonne Barr at the Middlesex Hospital in London with the virus being named Epstein-Barr virus (EBV) after its discoverers.

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Viruses: The Invisible Enemy, second edition

What are viruses for?

What are viruses for? What use are they? These are questions that my frustrated grandson asked during the first lockdown in 2020, when he was deprived of friends, school and sports, all because of a virus.

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A brief history of HIV [excerpt]

The first of December is World AIDS Day: a day to show support for those living with HIV, to commemorate those we have lost, and ultimately unite in the fight against HIV. To combat this pandemic though, we need to understand how the virus – and the wider virus group – reacts with the human body. In the following excerpt from Virus Hunt, Dorothy H. Crawford discusses the discovery and history of HIV and the retrovirus family.

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World AIDS Day reading list

World AIDS Day is a global campaign that raises awareness and funds for the estimated 34 million people living with HIV, and also commemorates the 35 million people who have died of the virus. The first one was held in 1988 and, as such, it is the longest running health day. Despite many medical advances, HIV remains one of the most devastating epidemics in human history.

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HIV/AIDS: How to stop the unstoppable?

By Dorothy H. Crawford
It is over 100 years since HIV, the AIDS virus, began spreading in humans. It all started in West Central Africa where, scientists calculate, HIV jumped from chimpanzees to humans around 1900. Then in 1964 the virus made its first trans-continental flight. In one move it leaped from Kinshasa, capital of the Democratic Republic of Congo, to the Caribbean island of Hispaniola. Here it established a foot-hold in Haiti before travelling on to the US in 1969. So began a journey that took HIV to virtually every country in the world, eventually infecting 65 million people, a figure that is rising by around three million annually.

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It’s only a virus

By Dorothy H. Crawford
“It’s only a virus.” How often do GPs utter those words over the course of a working day? They mean, of course, that your symptoms are mild, non-specific and don’t warrant any treatment. If you just go home and rest you’ll recover in a few days.

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The hunt for the origin of HIV

The month of May is home both to World Aids Vaccine Day (also known as HIV Vaccine Awareness Day) and the anniversary of the discovery of the AIDS virus itself. But how much do we know about where the HIV virus actually came from, and how it spread to become the global killer it is today? We spoke with Dorothy H. Crawford, author of Virus Hunt: The search for the origin of HIV, about the HIV virus and its history.

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