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Immune profiling of tumors may better stage early cancers

When immune cells infiltrate tumors in large numbers, patients do better. Now researchers aim to harness this immune response to predict outcomes. The Society for Immunotherapy of Cancer (SITC) in Milwaukee is coordinating an international effort to validate Immunoscore, an assay that quantifies this immune response.

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When politicians talk science

With more candidates entering the 2016 presidential race weekly, how do we decide which one deserves our vote? Is a good sense of humor important? Should she be someone we can imagine drinking beer with? Does he share our position on an issue that trumps all others in our minds? We use myriad criteria to make voting decisions, but one of the most important for me is whether the candidate carefully considers all the evidence bearing on the positions he advocates.

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Look away now: The prophecies of Nostradamus

If you like your prophecies pin sharp then look away now. The 16th century celebrity seer Nostradamus excelled at the exact opposite, couching his predictions in terms so vague as to be largely meaningless. This has not, however, prevented his soothsayings attracting enormous and unending interest, and his book – Les Propheties – has rarely been out of print since it was first published 460 years ago. Uniquely, for a renaissance augur, the writings of Nostradamus are perhaps as popular today as they were four and a half centuries ago.

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African health leaders claiming the future

Health leaders in sub Saharan African countries face some of the most demanding challenges anywhere in the world. Disease, poverty, the legacy of colonialism and, all too often, conflict, corruption and political instability, combine to make improving health extraordinarily difficult. Looking back we can see many great African health leaders who have played their part as the following few examples show.

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Can schizophrenia really be treated by “talk therapy” alone?

A recent study published by psychologist Anthony Morrison and colleagues in the British medical journal, The Lancet, is stirring up a long-standing debate about the treatment of schizophrenia. The article describes a randomized controlled trial with people diagnosed with schizophrenia who refused to take psychiatric medications called “antipsychotics.” The researchers tested whether these patients could be treated with a form of talk therapy called cognitive-behavioral therapy (CBT) in lieu of medications.

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Elisabeth Bing and an American revolution in birth

On May 15, Elisabeth Bing died at the age of 100. It is no exaggeration to say that during her long life she perhaps did more than any other individual to humanize childbirth practices in the United States. Obituaries and tributes to her rightly celebrate her role as a founding mother of the Lamaze movement in America and a lifelong advocate for improvement in maternity care.

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Oxford Medicine Online

Palliative care around the world

With a failing NHS and an ageing population in Britain, palliative care is a topic currently at the forefront of healthcare debate. Whether to abandon treatment in favour of palliation, is a challenging decision with profound implications for end-of-life care.

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Just a face in the crowd

The widespread practice of uploading photographs onto internet social networking and commercial sites has converged with advances in face recognition technologies to create a situation where an individual can no longer be just a face in the crowd. Despite the intrusive potential of face recognition technologies (FRT), the unauthorised application of such technologies to online digital images so as to obtain identity information is neither specifically prohibited nor a critical part of the international law reform discourse.

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The Jurassic world of … dinosaurs?

The latest incarnation (I chose that word advisedly!) of the Jurassic Park franchise has been breaking box-office records and garnering mixed reviews from the critics. On the positive side the film is regarded as scary, entertaining, and a bit comedic at times (isn’t that what most movies are supposed to be?). On the negative side the plot is described as rather ‘thin’, the human characters two-dimensional, and the scientific content (prehistoric animals) unreliable, inaccurate, or lacking entirely in credibility.

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50 shades of touch

Disgusting or delighting, exciting or boring, sensual or expected, no matter what you think about it, 50 Shades of Grey is certainly not a movie that passes by without leaving a mark on your skin. Based on E.L. James’ novel (honestly, somehow even more breathtaking than the movie), it tells the story of the complicated relationship between the dominant multi-millionaire Christian Grey, and the newly graduated, inexperienced, and shy, Ana Steele.

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What 4,000 years of hallucinations have taught us about our brain

Over the past forty years, many of my students have shared their personal experiences with hallucinogenic drugs. They are typically more fascinated, than frightened, by the experience. About sixty years ago the scientist C.H.W. Horne commented that “It is remarkable that one characteristic which seems to separate man from the allegedly lower animals is a recurring desire to escape from reality.”

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Why do we eat?

At first pass, the answer is obvious—to obtain energy to support our everyday activities and ultimately, to promote our survival. However, many of our modern day food choices suggest another answer, one that actually stands to threaten our health and functioning.

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From Galileo to Rosetta

For some people, recent images of the Rosetta space program have been slightly disappointing. We expected to see the nucleus of the Churyumov-Gerasimenko comet as a brilliantly shining body. Instead, images from Rosetta are as black as a lump of coal. Galileo Galilei would be among those not to share this sense of disappointment.

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Using web search data to study elections: Q&A with Alex Street

Social scientists made important contributions towards improving the conduct and administration of elections. A paper recently published in Political Analysis continues that tradition, and introduces the use of web search data to the study of public administration and public policy.

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Oxford Medicine Online

World Blood Donor Day 2015: blood types [infographic]

World Blood Donor Day 2015 is celebrated on 14 June each year. This Sunday, the theme is “Thank you for saving my life,” a chance for everyone who has benefited from a blood donation to thank the donors that selflessly donated to the cause. The demand for blood is always high as the shelf life of donated blood is only 42 days.

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