Oxford University Press's
Academic Insights for the Thinking World

Curcumin: common dietary supplement turned anti-cancer compound?

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies in the world. It is currently the third leading cause of cancer-related deaths in the United States and is projected to become the second leading cause of cancer-related deaths as early as 2030. Although recent advancements in cancer treatments have improved the overall outcome […]

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In memoriam: Ray Guillery

The seventh of April 2017 brought with it the sad passing of Ray Guillery FRS, celebrated neurophysiologist and neuroanatomist, world leader in thalamo-cortical communication, and Dr Lee’s professor of anatomy and fellow of Hertford College, Oxford, from 1984 to 1996. Dr Lizzie Burns kindly shares her memories of working with Ray on his final book, The Brain as a Tool, for which she was the illustrator.

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Multiple choice questions for the MRCP Part 1 [quiz]

The MRCP (UK) Part 1 exam set by the Royal College of Physicians is designed to test doctors on a wide range of topics to determine if they have the required level of knowledge to begin their postgraduate training as physician. The exam, which is sat over one day and features 200 multiple-choice (best of five) questions, can first seem very daunting; that’s why we’ve created this quiz to fit easily into your revision schedule.

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Are you the favorite child? The science of favoritism

We are frequently asked why we spend our professional careers studying favoritism, after all, parents don’t really have favorites. Or do they? A woman recently approached us after a lecture we gave and told us about caring for her aging mother. Her story captures the importance of this issue. She visited her mother daily in the final year of her mother’s life to feed, bathe, and care for her.

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What can we all do to tackle antibiotic resistance?

Welcome to the Oxford Journals guide to antibiotic resistance. 13th – 19th November marks World Antibiotic Awareness Week, an annual international campaign set up by the World Health Organisation (WHO) to combat the spread of antibiotic resistance, and raise awareness of the potential consequences. Even better, it’s not just scientists, politicians, and medical professionals who can work towards a solution

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The history of medical ethics

On the 20th of August 1947, 16 German physicians were found guilty of heinous crimes against humanity. They had been willing participants in one of the largest examples of ethnic cleansing in modern history. During the Second World War, these Nazi doctors had conducted pseudoscientific medical experiments upon concentration camp prisoners and the stories that unfolded during their trial

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National Family Caregivers (NFC) Month: a reading list

National Family Caregivers (NFC) Month is celebrated each November, in honor and recognition of the roughly 40 million Americans providing care to an adult family member or loved one. In 1997 President William J. Clinton signed the first NFC Month Presidential Proclamation, articulating that “Selflessly offering their energy and love to those in need, family caregivers have earned our heartfelt gratitude and profound respect.”

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The history of Acupuncture [timeline]

With its roots stretching back to over 6,000 years BCE, Acupuncture is one of the world’s oldest medical practices. This practice of inserting fine needles into specific areas of the body to ‘stimulate sensory nerves under the skin and in the muscles of the body’ is used widely on a global scale to alleviate pain caused by a variety of conditions.

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Herpes and human evolution: a suitable topic for dinner?

Politics and religion are always topics best avoided at dinner and it’s perhaps not too much of a stretch to add STIs to that list. But it was over dinner at King’s College, Cambridge that my colleagues Charlotte Houldcroft, Krishna Kumar, and I first started to talk about the fascinating relationship humans have with Herpes.

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Pain medicine and addiction: A reading list

On the 10 August 2017, President Donald Trump declared a ‘national emergency’ in the United States – the cause: the country’s escalating opioid epidemic. This drug crisis has rapidly become one of the worst in American history, with data showing that in 2016 up to 65,000 people died from drug overdoses. Officials state that for citizens under 50 they are the leading cause of death, and opioid-specific overdoses make up two-thirds of all those recorded.

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Can microbiology tell us exactly what killed the Aztecs?

The arrival of the Spanish conquistadors to Mexico in the 1620s marked the beginning of the end for the indigenous people. With an estimated population of between 15 and 30 million at this point, this dropped dramatically to only two million by 1700: the result of battles, famine, drought, and perhaps most significantly, infectious diseases. The following Q&A investigates how microbiology contributed to the ruin of the once-flourishing Mesoamerican culture.

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Marketing-driven government (Part 2)

When marketing is used in government, its impact is often limited because it is dogged by a short-term, fragmented approach influenced by political time cycles. Government marketing is often characterised by an overemphasis on broadcast communications, including digital platforms, to the exclusion of a more citizen-centric approach focused on listening, relationship building, and social networking.

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Marketing-driven government (Part 1)

Marketing is an approach to social programme design and delivery that should underpin how governments and not-for-profit agencies develop and select policy, shape how services are delivered, and build sustained partnerships with citizens and other stakeholder organisations. However, marketing is a very often misunderstood and misapplied within Government

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Are we losing a generation of younger doctors?

We live in challenging times for physicians, who are required to do things that are wearing them out and making them feel bad about their jobs. Surveys showing large percentages of doctors burned out, dissatisfied with their work or regretting their career choice point to something deeply psychological that is happening to many doctors—something that should make all of us very concerned.

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Invest in food security; end hunger

World Food Day is celebrated on 16th October each year, commemorating the founding of the Food and Agriculture Organization of the United Nations (FAO). Various events take place around the world, promoting worldwide awareness and action for those who suffer from hunger, and the need to ensure food security and nutrition for everyone. Some of the statistics provided by the FAO are staggering:

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Understanding physician-assisted death [excerpt]

When it comes to end-of-life treatment, patients currently have a few different options available to them. One option, refusal of treatment, is when a decisionally capable patient is put in the driver’s seat with respect to medical treatment under the doctrine of informed consent. Another option is pain management, where palliative medicine is administered to entirely eliminate, or reduce pain to a level that the patient finds tolerable.

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