Oxford University Press's
Academic Insights for the Thinking World

  • Author: Gary L. Wenk

How olive oil promotes brain health

Diets and superfoods are all the rage. From acai berries to the Zone diet, many a dietary trend has come along promising a range of benefits, such as weight loss, heart health, and improved cognition. But the science behind these claims is often sketchy at best. One dietary regime that has stood the test of […]

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How a failed suicide affects the brain

The numerous factors that induce someone to think about suicide, the “ideators,” are often different from those who actually attempt suicide, the “attempters.” For example, the traditional risk factors for suicide, such as depression, hopelessness, many psychiatric disorders, and impulsivity, strongly predict suicide ideation but weakly predict suicide attempts among ideators.

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Why do I wake up every morning feeling so tired?

The alarm rings, you awaken, and you are still drowsy: why? Being sleepy in the morning does not make any sense; after all, you have just been asleep for the past eight hours. Shouldn’t you wake up refreshed, aroused, and attentive? No, and there are a series of ways to explain why. The neurobiological answer: During the previous few hours before waking in the morning, you have spent most of your time in REM sleep, dreaming.

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Why are we all so frightened?

Knowing what you should fear, and quickly recognizing the biological changes in your body that indicate fear, can save your life. This critical task is processed by a small almond-shaped structure, the amygdala, which lies deep within the bottom of the brain, not far from your ears. The amygdala receives information from many brain regions, your internal organs, and external sensory systems, such as your eyes and ears.

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The romance of chocolate

Is chocolate an aphrodisiac? Gifts of chocolate are given usually with that intent at this time of the year. Does it work? Well, maybe; gastronomy is known as the sister art of love. Women often crave chocolate. In 1648, according to the diary of English Jesuit Thomas Gage, the women of Chiapas Real arranged for the murder of a certain bishop who forbade them to drink chocolate during mass.

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Why you must stop for coffee and donuts this morning

Sometimes, what your brain wants is not always good for your body. Donuts are a good example. It’s early morning and you’re driving to work after a nice breakfast of black coffee and two eggs, easy-over, with bacon. Yet, you’re still hungry and having difficulty paying attention to the traffic. Why? Your brain is not cooperating because it is not satisfied with that breakfast because it lacked one critical ingredient that your brain urgently needs: sugar.

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A magical elixir for the mind

The brain is a product of its complex and multi-million year history of solving the problems of survival for its host, you, in an ever-changing environment. Overall, your brain is fairly fast but not too efficient, which is probably why so many of us utilize stimulants such as coffee and nicotine to perform tasks more efficiently. Thus far, no one has been able to design a therapy that can make a person truly smarter.

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What 4,000 years of hallucinations have taught us about our brain

Over the past forty years, many of my students have shared their personal experiences with hallucinogenic drugs. They are typically more fascinated, than frightened, by the experience. About sixty years ago the scientist C.H.W. Horne commented that “It is remarkable that one characteristic which seems to separate man from the allegedly lower animals is a recurring desire to escape from reality.”

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How do gut bugs affect brain health?

Our brain lives in a symbiotic relationship with the bugs in our gut. Whatever we eat, they eat. In return, they help our brain function optimally in a variety of ways. During the past few years, it has become increasingly apparent that in the absence of bacteria humans would never have evolved to our current level of cognitive performance. Our brains are profoundly dependent upon a wide range of chemicals produced by these gut bugs.

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Can your diet make you feel depressed?

I am often asked whether eating particular foods can enhance mood and treat the symptoms of depression. With very few exceptions, the answer is no. In contrast, our mood can be easily depressed by our diet. Why? For adults, the brain responds primarily to deficits, not surpluses, in the diet.

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How does food affect your mood?

Considerable evidence has linked an unhealthy diet to obesity, metabolic syndrome, diabetes and cancer. We now understand how chronic obesity ages us and then underlies the foundation of our death. Furthermore, obesity leads to body-wide chronic inflammation that predisposes us to depression and dementia. However, these are all the long-term consequences of our diet upon our body and brain.

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The role of marijuana in your coffee addiction

Does coffee enhance marijuana? A study published recently in the Journal of Neuroscience by neuroscientists from the Integrative Neurobiology Section of the National Institute on Drug Abuse, a branch of the National Institutes of Health, has finally provided a definitive answer: Yes, No, and it depends.

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Can marijuana prevent memory decline?

Can smoking marijuana prevent the memory loss associated with normal aging or Alzheimer’s disease? This is a question that I have been investigating for the past ten years. The concept of medical marijuana is not a new one. A Chinese pharmacy book, written about 2737 BCE, was probably the first to mention its use as a medicine for the treatment of gout, rheumatism, malaria, constipation, and (ironically) absent-mindedness.

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Is caffeine a gateway drug to cocaine?

Caffeine is the world’s most commonly abused brain stimulant. Daily caffeine consumption by adolescents (ages 9-17 years) has been rapidly increasing most often in the form of soda, energy drinks, and coffee. A few years ago, a pair of studies documented that caffeine consumption in young adults directly correlated with increased illicit drug use and generally […]

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Is chocolate better than exercise for the brain?

Everyone knows that aerobic exercise is good for the body, but is it always as good for brain? Furthermore, is exercise better than eating lots of chocolate for the aging brain? A recent study published in the journal Nature Neuroscience by a group of scientists from Columbia University and NYU gave a large daily dose […]

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Does marijuana produce an amotivational syndrome?

Does marijuana produce an amotivational syndrome? Whether the amotivational syndrome exists or not is still controversial; there are still too few poorly controlled small studies that don’t allow a definitive answer. Most people who use marijuana don’t develop this syndrome.

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