Comments on: Potential Role of Vitamin D in Multiple Sclerosis http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/ Academic insights for the thinking world. Thu, 09 Feb 2012 20:48:00 +0000 http://wordpress.org/?v=2.9.2 hourly 1 By: A Hot 100 of Vitamin D Articles http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/comment-page-1/#comment-152703 A Hot 100 of Vitamin D Articles Mon, 20 Jul 2009 08:26:58 +0000 http://blog.oup.com/?p=4633#comment-152703 [...] Potential Role of Vitamin D in Multiple Sclerosis OUPblog - New York,New York,USA Vitamin D supplements are appropriate to restore their levels to within normal range. This should be considered a general medical recommendation simply to … Not sure - supposedly based on a book written by a doctor, this one really does blatantly set out to sell you vitamin D tablets to combat MS. Oh yes, the reference to OUP has nothing to do with ‘the’ Oxford University Press. [...] [...] Potential Role of Vitamin D in Multiple Sclerosis OUPblog – New York,New York,USA Vitamin D supplements are appropriate to restore their levels to within normal range. This should be considered a general medical recommendation simply to … Not sure – supposedly based on a book written by a doctor, this one really does blatantly set out to sell you vitamin D tablets to combat MS. Oh yes, the reference to OUP has nothing to do with ‘the’ Oxford University Press. [...]

]]> By: Milton Hare http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/comment-page-1/#comment-151920 Milton Hare Wed, 03 Jun 2009 22:18:19 +0000 http://blog.oup.com/?p=4633#comment-151920 The correlation between Vitamin D deficiency and MS is well-established. For a recently-diagnosed patient, a suitable protocol would involve rapidly establishing a high serum level of 80-100 ng/ml of Vitamin D3 either by injection (British nursing home physicians routinely provide doses of 600,000 iu in a single injection) or by a rapid loading phase, 50,000 iu every two days for three weeks, then level out to 10,000 iu per week for six weeks and then provide a 25 hydroxyvitamin D test [25(OH)D test] followed by appropriate increase or decrease in daily dosage. An individual I am familiar with has taken 10,000 iu per day + 600 mg calcium, 300 mg magnesium, 10 mg zinc per day for longer than three years. Her MS symptoms (left leg gait disturbance) do not appear to have progressed over a five-year period. She is taking other MS medication as well. In the long term, 10,000 iu per day of Vitamin D3 should achieve a serum level from 80 to 120 ng/ml - ideal for an MS patient. 200 ng/ml is probably the lowest dose associated with excess calcium in the urine, which would be the first sign of an excessive dose. R. Vieth wrote a survey of dosage studies involving 40,000 iu Vitamin D3 per day and found no reports of toxicity, concluding that 10,000 iu/day is safe. There are suggestions in the literature that direct sun exposure provides additional benefits to MS patients, not related directly to Vitamin D3. Sunbathing may by some different mechanism. Whatever course you take, your Vitamin D3 dosage should be quite high - 10,000 iu should not cause harmful side-effects. I am a layman; my comments are based on my reading of the medical literature. Key sources: H F Deluca, M Holick, R Vieth, P Goldberg, M Catorna. A good layman's site is www.vitamindcouncil.org. The correlation between Vitamin D deficiency and MS is well-established. For a recently-diagnosed patient, a suitable protocol would involve rapidly establishing a high serum level of 80-100 ng/ml of Vitamin D3 either by injection (British nursing home physicians routinely provide doses of 600,000 iu in a single injection) or by a rapid loading phase, 50,000 iu every two days for three weeks, then level out to 10,000 iu per week for six weeks and then provide a 25 hydroxyvitamin D test [25(OH)D test] followed by appropriate increase or decrease in daily dosage. An individual I am familiar with has taken 10,000 iu per day + 600 mg calcium, 300 mg magnesium, 10 mg zinc per day for longer than three years. Her MS symptoms (left leg gait disturbance) do not appear to have progressed over a five-year period. She is taking other MS medication as well. In the long term, 10,000 iu per day of Vitamin D3 should achieve a serum level from 80 to 120 ng/ml – ideal for an MS patient. 200 ng/ml is probably the lowest dose associated with excess calcium in the urine, which would be the first sign of an excessive dose. R. Vieth wrote a survey of dosage studies involving 40,000 iu Vitamin D3 per day and found no reports of toxicity, concluding that 10,000 iu/day is safe. There are suggestions in the literature that direct sun exposure provides additional benefits to MS patients, not related directly to Vitamin D3. Sunbathing may by some different mechanism. Whatever course you take, your Vitamin D3 dosage should be quite high – 10,000 iu should not cause harmful side-effects. I am a layman; my comments are based on my reading of the medical literature. Key sources: H F Deluca, M Holick, R Vieth, P Goldberg, M Catorna. A good layman’s site is http://www.vitamindcouncil.org.

]]> By: Stuart http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/comment-page-1/#comment-151908 Stuart Wed, 03 Jun 2009 01:44:25 +0000 http://blog.oup.com/?p=4633#comment-151908 Learn more of Multiple Sclerosis when registered at: <a>http://www.msviewsandnews.org</a>. Once registered, you will receive our weekly ms related e-newsletter, keeping you informed of current MS information. And when you can, use our MS Blog: <a>http://wwwmsviewsandrelatednews.blogspot.com</a>/ - to your advantage. Have questions? write to: <a>stuart@msviewsandnews.org</a> - Please don't forget to inform others whom you know that are affected by MS, of this information. Thank you Learn more of Multiple Sclerosis when registered at: http://www.msviewsandnews.org.

Once registered, you will receive our weekly ms related e-newsletter, keeping you informed of current MS information.

And when you can, use our MS Blog: http://wwwmsviewsandrelatednews.blogspot.com/ – to your advantage.

Have questions? write to: stuart@msviewsandnews.org -

Please don’t forget to inform others whom you know that are affected by MS, of this information.

Thank you

]]> By: Nancy B http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/comment-page-1/#comment-151878 Nancy B Tue, 02 Jun 2009 01:14:55 +0000 http://blog.oup.com/?p=4633#comment-151878 My neurologist tested my Vitamin D level while I was having difficulty with balance, numbness in my face and limbs. I was also having difficulty sleeping and cognitive/memory issues. The blood test determined I was severely deficient in Vitamin D. He asked me to start taking 2000IU gel caps 23 years ago. I can only hope that Vitamin D supplements are the answer to solve the MS diagnosis mystery. For now, I'm a believer and I am anxious to see what my follow-up MRI of my head shows next month. If your doctor has not checked your levels, have him do so. It could make a huger difference with your symptoms. My neurologist tested my Vitamin D level while I was having difficulty with balance, numbness in my face and limbs. I was also having difficulty sleeping and cognitive/memory issues. The blood test determined I was severely deficient in Vitamin D. He asked me to start taking 2000IU gel caps 23 years ago. I can only hope that Vitamin D supplements are the answer to solve the MS diagnosis mystery. For now, I’m a believer and I am anxious to see what my follow-up MRI of my head shows next month. If your doctor has not checked your levels, have him do so. It could make a huger difference with your symptoms.

]]> By: Pete http://blog.oup.com/2009/06/vitamin-d-multiple-sclerosis/comment-page-1/#comment-151871 Pete Mon, 01 Jun 2009 21:51:15 +0000 http://blog.oup.com/?p=4633#comment-151871 As the resent research on vitamin and MS used an dose of 14000IU a day, on average, for a year with absolutely no sign of overdose, it appears that the optimum dose is higher than 3000IU a day. As the resent research on vitamin and MS used an dose of 14000IU a day, on average, for a year with absolutely no sign of overdose, it appears that the optimum dose is higher than 3000IU a day.

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